PQQ For Energy, Mental Health & Inflammatory Pain

Happy Self.


PQQ is a recently discovered compound which will be classified as something like a vitamin when all the research is in. However, the alt health community already understand the vital role this nutrient is playing with regards our health.

PQQ is pivotally important for the following:

  • Mitochondria
  • Sleep
  • Gut
  • Stress levels


PQQ is possibly the ultimate spark of life in the Universe. It is found in intergalactic dust as well as within virtually every living organism and it plays a critical part in the health of our Mitochondria.

The role PPQ plays in relation to our Mitochondria is to protect them from damage, thereby ensuring the Mitochondria are able to keep on producing ATP.

ATP is the energy which powers our body.

PQQ is neuro-protective, protecting brain cells from oxidative damage. It promotes nerve growth factor and has proven to be memory restorative in animal and human studies.

PQQ & Co Enzyme Q-10

PQQ & Co Enzyme Q-10 work very much in synergy with each other. Co Q-10, as Co Enzyme Q-10 is often referred to, is vital for our Mitochondrial function in terms of energy production.

PQQ is vital for it’s protective action, and the two constituents working in synergy are more beneficial than when being used on their own.

In human and animal studies the neuro-protective influence these two agents were seen to exert was significant, improving brain function considerably in each at a dosage level of 20mg PQQ and 300mg of Co Q10

PQQ on it’s own will increase energy production but this is further improved with the introduction of Co Q10.

The body produces enough Co Q10 when we are younger, as long as we’re eating a relatively healthy diet, but it’s ability to produce enough after the age of 40 is impaired, and so supplementation is recommended by health professionals.

PQQ As An Antioxidant

Oxidative stress is what ages us and damages us at a cellular level, thereby compromising our overall health. Compounds exerting oxidative stress are said to be performing a catalytic cycle.

PQQ has some broad spectrum antioxidant activity which has the ability to be recycled many times over. By contrast, Vitamin C is a brilliant antioxidant, but it can only be used 4 times to the 20,000 times PPQ will show up to protect us at a cellular level. This effectively means it can perform 20,000 catalytic cycles before it is completely spent.

PQQ & Immune Function

Things like our immune function have high metabolic needs, as does our heart and brain. PQQ provides the protections needed for the body to perform optimally.

It is this protective action against ageing and degeneration caused by environmental toxins which reveal how useful it is already, but also will be, with the growing number of Neurodegenerative diseases which are sky rocketing in incidence as well as cases.

Most of the research conducted so far has been done on the brain in terms of the anti-inflammatory properties of PQQ and the degeneration in the brain.

PQQ has been shown to protect against every known toxin in the brain and is especially protective against heavy metals and glutamate which has strong correlations with Parkinson’s Disease.

PQQ is a potent protective agent which prevents the development of compounds which cause all forms of degeneration in the brain. Beta-Amyloid, which is strongly associated with Alzheimer’s, and Alpha Synuclein, which is also associated with Parkinson’s.

***Resveratrol, which is found in high amounts in Blueberries, affects the same Alpha Synuclein pathways in the brain and provides similar protections as PQQ. However, like PQQ we cannot get enough Resveratrol in the diet to achieve any therapeutic benefit. For this we need around 500mg of Resveratrol to be effective.

Dr. Michael Murray, ND, who is a leading authority in PQQ, says we will achieve better results with much lower levels of PQQ than with higher levels of Resveratrol.

PQQ & Inflammation

PQQ is highly anti-inflammatory. Inflammation is the precursor to all serious illness so anything which reduces inflammation is critical.

PQQ, at therapeutic doses, has been shown to reduce the inflammatory agent C-reactive protein, (CRP), by as much as 50%. CRP is a substance produced by the Liver in response to inflammation.

***There are also many essential oils which are highly anti-inflammatory. Learn more here: Essential Oils For Inflammation

PQQ For Anxiety & Depression

Inflammatory markers are strongly associated with anxiety and mental health issues, the higher the levels of inflammation in the body, the more likely we are to suffer from anxiety, panic attacks and depression. There is no question that the neuroprotective capabilities of PQQ, especially in conjunction with Co Q Enzyme 10, will have a very positive effect on most people suffering from these debilitating conditions.

A lot of products which calm us down and make us less stressed also have a sleepy component to their effectiveness. But PQQ is the opposite. PQQ is anti-anxiety and it improves energy levels as well as brain function! This is going to provide a massive breakthrough for people who feel like they have only been half alive due to medicating their stress, anxiety and depression for a long time!

PQQ has also been shown to help with OCD also.

Learn how to manage anxiety.

PQQ For Sleep

PQQ improves sleep quality, probably because it is returning everything with the body to a much more ‘normal’ state. Homoeostasis is what is needed for a good nights sleep.

We heal when we are asleep, so the improved quality of sleep we achieve with better levels of PQQ means that we are healing and maintaining our health much more effectively.

This means we are on a great upward spiral all of a sudden.

PQQ & The Microbiome

These days the gut is considered to be out first brain, with our heart being our second, and the organ inside our head being relegated to third position.

Not enough is known about PQQ to conclusively determine which influences on the body are leading to the ultimate improvements in cognitive function, but Michael Murray, ND, whose work this article is based on, postulates that in all likelihood, we will discover hard proof in the near future to show that the benefits reaped in the brian will have originated in the gut.

In the article Gut Health, I explain how our gut health is paramount, and how poor gut health will soon lead to many other painful and serious conditions, not least full body inflammation and anxiety and depression.

People suffering from Anxiety and Depression are much more likely to develop neurodegenerative diseases, and this is probably why!

PQQ & Gut & Liver Health

The Western diet is causing many of us to develop gut issues. Diagnoses of IBS are through the roof, but the incidence of previously unheard of conditions like, Diverticulitis, Ulcerative Colitis, and Crohn’s Disease etc are all on a massive upward trajectory.

PQQ has been shown in animal studies to reverse all of the damage of a Western diet, which includes reversing fatty liver and preventing even more serious liver issues, as well as tackling disbiosis and reduced immunity, along with healing leaky gut with it’s attendant inflammatory symptoms.

PQQ Foods

Because of soil depletion, and our modern Western diet, we are not getting anywhere near enough PQQ in our diets, even though we only need it in microgram amounts, like Folic Acid etc.

  • Kiwi fruit (high amounts)
  • All green leafy vegetables
  • Parsley
  • Green peppers
  • Papaya
  • Spices

*Kiwis are high in Oxalates, which some people have issues with. Parsley is the same. Oxalic Acid forms kidney stones, but will also cause allergic reactions, like pain in the feet etc.

***This, however, is a microbiome issue, so supplementing with the right enzymes is important here. Oxalate reducing enzyme is what we need to process Oxalic Acid, thereby reducing the risk of kidney stones and crystals forming in the soft tissue, which can be very dangerous.

This is why gut health is fundamental to our overall health!

PQQ Dosage

PQQ is produced naturally via a process of fermentation, but it can also be synthesised. The body doesn’t like anything fake, so stick to the naturally fermented options. It pays to know how your supplements are made!

PQQ becomes beneficial within a range of 5mg to 20mg in terms of therapeutic benefits.

Because we produce Co Q10 reasonably effectively until around our 40’s we should only be supplementing with PQQ until this time. After 40 we would all be wise to supplement with Co Q10 also.

After the age of 40 a good maintenance dose of both PQQ and Co Q10 would be 20mg PQQ and 300mg of Co Q10. However, no two people are the same, so it’s important to experiment with what feels best for you.

IMPORTANT: Statins have a deleterious effect on Co Q10. Because Stains are prescribed for older people this is disastrous! With Co Q10 naturally diminishing already, the situation is further compounded by the use of Statins.

Is it any wonder we are feeling more tired and run down with all of these medications which interfere with the natural processes of the body in such profoundly destructive ways?

And Get This :: There is not one single shred of proof that Statins do any good, whatsoever, in women. WOMEN SHOULD NEVER BE PRESCRIBED STATINS!

However, your doctor will, in all likelihood, get financial incentives for prescribing Statins, and so you’ll be offered them by some doctors even though they are going to adversely affect your health.

Just SAY NO, like Nancy Reagan told us to!

And The Good News? :: PQQ has been proven to be as effective as Statins in reducing cholesterol in men, which it probably achieves due to it’s interaction with the stress hormone Cortisol.

Cortisol is one of the best anti-inflammatories out there… so the ability of PQQ to somehow help regulate total body function, thereby supporting improved homeostasis, eliminates the need for these dangerous drugs.

PQQ has been seen to lower total body cholesterol and LDL cholesterol, thereby reducing blood lipids to the same levels of Statins, but by using a completely different mechanism.

*This was achieved after 12 weeks with a 20mg dose per day.

I use both PQQ and Co Q10 from Swiss Bioenergetics. I do not receive any benefits for mentioning this.

QCo Enzyme Q10


The information provided is not intended to replace the medical directives of your healthcare provider. This information is not meant for the diagnosis of health issues. If you are pregnant, have serious or multiple health concerns, consult with your healthcare provider before using essential oils or associated products. If you experience any complications or adverse reactions contact your healthcare provider.

Deepen your knowledge by using the Wild As The Wind Recommended Resources

Another resource you may find useful can be found by following the link below. *Please note, I use sources from the Recommended Resources list as well as sources from the Healthcare and Skincare Information Sources list when researching articles for the Wild As The Wind Blog.

Best Healthcare and Skincare Information Sources.

Wild As The Wind use a number of resources when deciding which essential oil formulas to put together for optimal healing and efficacy, as well as to support any health claims we may make.

We use the industry ‘bible’ on essential oil safety: Essential Oil Safety: A Guide for Health Care Professionals [2nd Edition] by Robert Tisserand and Rodney Young, to establish the safety of the Wild As The Wind formulations.

We owe a particular debt to Hyla Cass for her tireless work with Hemp Essential Oil as well as GreenMedInfo, and, of course, the teachings of Penny Price and Patricia Davis.

Many of the scientific studies used to inform the claims made on this website are via GreenMedInfo, as well as via Dr. Josh Axe, Ty Bollinger on the Truth About Cancer website as well as, on the odd occasion, Dr. Eric Zielinski

Other resources include:

  • PubMed
  • WebMD
  • Robert Tisserand
  • Dr. Robert Pappas
  • AromaWeb
About Rachel Wild

Rachel Wild is the Creative Director at Wild As The Wind. She's been a professional writer for print and digital publication for more years than she cares to remember. She is no longer a 'writer for rent', now very gratefully, devoting all of her time to her passion... writing about health and well-being and sharing it as far and wide as she can. (Please help her!)

Rachel passionately supports creative endeavour and independent thinking. "The future, if it's good, will see a triumph of quality over quantity, substance over style and give rise to truly inspired thinking born of fearlessness and compassion."

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